A thorough review of developments and innovations in floating tablet medication delivery systems
Akanksha Khairnar
, Dr. R.K Surwase
Key words: GI tract, both dry and wet granulation, pharmaceuticals, pills that float, and medication delivery method
Floating tablets, commonly referred as gastroretentive GRDDS, or new formulations are used in medicine delivery systems. intended to prolong the duration of the pharmaceutical within the digestive system, especially the abdomen. For medications that require extended action or the optimal window for upper gastrointestinal absorption, this approach is quite beneficial.
absorption within a particular pH range. The floating mechanism provides regulated medication release, lowering dosage frequency, and enhances bioavailability and therapeutic efficacy. Gas-forming and hydrophilic polymers substances, such as Bicarbonate of sodium, are commonly included within the manufacture of floating tablets to guarantee buoyancy in stomach juices. Key preparedness
Hot melt extrusion, moist granulation, and direct compression are some methods. For drugs like Ofloxacin and furosemide, both of which have limited either absorption or heavily digested in the initial pass, these pills are beneficial. Additionally, floating pills have the potential to improve patient adherence, especially due to medications Having brief half-lives or those
needing a managed release. Notwithstanding These encouraging advantages, there are obstacles such inconsistent stomach buoyancy of the tablet, emptying, and complicated big-scale production. 3D printing and biodegradable polymers are two examples of material innovations that try to solve these problems. The growing prevalence of floating tablets is driving up market demand.
of long-term illnesses, particularly in places like India. In summary, floating tablets offer enhanced therapeutic outcomes for a variety of drugs and constitute a substantial progress in gastro-retentive drug administration; however, additional investigation and advancement is required in order to maximize composition also manufacture.
"A thorough review of developments and innovations in floating tablet medication delivery systems", JETNR - JOURNAL OF EMERGING TRENDS AND NOVEL RESEARCH (www.JETNR.org), ISSN:2984-9276, Vol.4, Issue 6, page no.b791-b797, June-2026, Available :https://rjpn.org/JETNR/papers/JETNR2606207.pdf
Volume 4
Issue 6,
June-2026
Pages : b791-b797
Paper Reg. ID: JETNR_235020
Published Paper Id: JETNR2606207
Downloads: 00046
Research Area: Pharmacy All
Country: manur,nashik, Maharastra, India
ISSN: 2984-9276 | IMPACT FACTOR: 9.87 Calculated By Google Scholar | ESTD YEAR: 2023
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.87 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: RJPN (IJPublication) Janvi Wave
