Aarti Chavan
, Yashpal M. More
Nanoemulgel, Nanoemulsion, Topical Drug Delivery, Lipophilic Drugs, Controlled Release, Skin Permeation, Bioavailability, Transdermal Delivery, Gelling Agents, Drug Delivery System
Nanoemulgel is an advanced topical drug delivery system developed by incorporating nanoemulsion into a gel base to improve the therapeutic efficacy of lipophilic drugs. A large number of newly developed drug molecules exhibit poor aqueous solubility, low bioavailability, and variable absorption, which limit their clinical effectiveness through conventional dosage forms. Nanoemulgel overcomes these limitations by combining the advantages of nanoemulsion, such as enhanced drug solubilization, improved skin permeation, and controlled release, with the favorable rheological properties of gels, including better spread ability, patient compliance, and prolonged retention at the site of application. The presence of nanosized droplets increases the surface area for absorption and facilitates penetration through the stratum corneum barrier. Nanoemulgel formulations generally contain oils, surfactants, co-surfactants, gelling agents, preservatives, antioxidants, and permeation enhancers. They are widely used for topical delivery of antifungal, anti-inflammatory, analgesic, and cosmetic agents. Various evaluation parameters such as particle size, viscosity, pH, drug content, in-vitro permeation, stability studies, and morphology are used to characterize the formulation. Due to its improved stability, controlled drug release, and enhanced patient acceptability, nanoemulgel has emerged as a promising carrier system for topical and transdermal drug delivery
Volume 4
Issue 6,
June-2026
Pages : a107-a112
Paper Reg. ID: JETNR_234708
Published Paper Id: JETNR2606019
Downloads: 00091
Research Area: Pharmacy All
Country: Nashik, Maharastra, India
ISSN: 2984-9276 | IMPACT FACTOR: 9.87 Calculated By Google Scholar | ESTD YEAR: 2023
An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.87 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator
Publisher: RJPN (IJPublication) Janvi Wave
