Advances in Monoclonal Antibody-Based Therapeutics: Production, Mechanisms, and Clinical Applications

Mr. Prathmesh Yadav , Mr . Umesh Kolap , Dr. Shobhraj Malavi

Monoclonal antibodies, Targeted therapy, Immunotherapy, Hybridoma technology, Antibody-drug conjugates, Autoimmune disease, Cancer treatment

Highly specific immunoglobulins made in laboratories, monoclonal antibodies (mAbs) are made to identify and bind to specific antigens. By offering focused therapy approaches for a variety of illnesses, such as cancer, autoimmune diseases, infectious diseases, and transplant rejection, they have transformed modern medicine. Monoclonal antibodies are categorized as naked, conjugated, and bispecific based on their structure and function. Numerous mechanisms, including antigen binding, neutralization of target molecules, immune response modulation, and activation of immune-mediated cytotoxicity, including complement-dependent and antibody-dependent cell-mediated cytotoxicity, are used by these agents to produce their therapeutic effects.Advanced biotechnological methods, such as hybridoma and recombinant DNA technology, are used to manufacture monoclonal antibodies, which are then purified using chromatographic procedures to guarantee excellent stability and purity.

Published Paper   E-Certificate

"Advances in Monoclonal Antibody-Based Therapeutics: Production, Mechanisms, and Clinical Applications", JETNR - JOURNAL OF EMERGING TRENDS AND NOVEL RESEARCH (www.JETNR.org), ISSN:2984-9276, Vol.4, Issue 4, page no.c785-c791, April-2026, Available :https://rjpn.org/JETNR/papers/JETNR2604367.pdf

Volume 4 Issue 4, April-2026

Pages : c785-c791

Paper Reg. ID: JETNR_234057

Published Paper Id: JETNR2604367

Downloads: 00011

Research Area: Humanities All

Country: Kolhapur, MAHARASHTRA, India

Published Paper PDF: https://rjpn.org/JETNR/papers/JETNR2604367

Published Paper URL: https://rjpn.org/JETNR/viewpaperforall?paper=JETNR2604367

ISSN: 2984-9276 | IMPACT FACTOR: 9.87 Calculated By Google Scholar | ESTD YEAR: 2023

An International Scholarly Open Access Journal, Peer-Reviewed, Refereed Journal Impact Factor 9.87 Calculate by Google Scholar and Semantic Scholar | AI-Powered Research Tool, Multidisciplinary, Monthly, Multilanguage Journal Indexing in All Major Database & Metadata, Citation Generator

Publisher: RJPN (IJPublication) Janvi Wave

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